Quercetin and Statin: interaction, severity and spacing
Quercetin and Statin interact because quercetin inhibits organic anion transporting polypeptide (OATP) transporters, which can modestly raise statin blood levels. Take them with care. Mild risk.
The interaction in detail
| Pair | Quercetin and Statin |
|---|---|
| Type | Nutrient interaction |
| Severity | Mild |
| Required spacing | None specified |
| Onset | At the time of dosing |
Mechanism
Quercetin inhibits organic anion transporting polypeptide (OATP) transporters, which can modestly raise statin blood levels.
What to do
Keep the quercetin dose consistent; report muscle aches or weakness.
How to fit both into one day
Quercetin absorbs best on a relatively empty stomach. Keep the dose consistent if you take prescription medication.
Cholesterol synthesis peaks overnight, so most statins are dosed in the evening. Avoid grapefruit, which raises drug levels.
Putting Quercetin in the morning and Statin in the evening satisfies the 0-hour separation without disrupting either one's absorption window.