Moderate interactionModerateSeparate by 3h
Iron bisglycinate and Fluoroquinolone antibiotic: interaction, severity and spacing
Iron bisglycinate and Fluoroquinolone antibiotic interact because iron forms insoluble complexes with fluoroquinolones, lowering antibiotic absorption. Take them 3 hours apart. Moderate risk.
Last reviewed: 2026-09-20Reviewed by: StackingRight clinical review
The interaction in detail
| Pair | Iron bisglycinate and Fluoroquinolone antibiotic |
|---|---|
| Type | Nutrient–drug interaction |
| Severity | Moderate |
| Required spacing | 3 hours minimum |
| Onset | At the time of dosing |
Mechanism
Iron forms insoluble complexes with fluoroquinolones, lowering antibiotic absorption.
What to do
Take the antibiotic 2 hours before or 6 hours after iron.
How to fit both into one day
Iron bisglycinate
morningempty stomach
Non-heme iron absorbs best on an empty stomach with vitamin C. Coffee, tea and calcium can halve absorption, so keep them two hours away.
Putting Iron bisglycinate in the morning and Fluoroquinolone antibiotic in the evening satisfies the 3-hour separation without disrupting either one's absorption window.