Fatty acid
Omega-3
Omega-3 requires 1100 mg daily for adult women and 1600 mg for men. It works best alongside Vitamin D3 softgel.
What Omega-3 does
Precursors to resolvins and protectins; supports membrane fluidity and cardiovascular function.
Target expressed as combined EPA+DHA intake. Absorption requires dietary fat.
How much you need
| Measure | Adult male | Adult female |
|---|---|---|
| Recommended intake | 1600 mg | 1100 mg |
| Upper intake level | None established | |
| Typical supplement dose | 1000-2000 mg combined · 100 g | |
Interactions involving Omega-3
3 sourced rules| Pair | Severity | Mechanism | Action |
|---|---|---|---|
| Fish oil (EPA/DHA) × Warfarin | Moderate | EPA and DHA displace arachidonic acid and reduce thromboxane production, which prolongs bleeding time on top of warfarin. | Doses up to 2 g combined EPA+DHA are usually tolerated; higher doses need prescriber awareness and INR check.Source |
| Fish oil (EPA/DHA) × Direct anticoagulant | Mild | Omega-3 fatty acids have mild platelet-inhibiting effects that add to anticoagulant action. | Keep doses moderate and flag any new bruising to your prescriber.Source |
| Vitamin D3 softgel × Fish oil (EPA/DHA) | Synergy | Both are fat-soluble and require dietary fat for micelle formation and lymphatic absorption. Taken with fat, each improves the other’s uptake. | Take vitamin D3 and fish oil in the same meal that contains at least 10-15 g of fat.Source |